Furthermore, despite the significant variation between the 3 tumors, each presented with chromothryptic events on chromosome 9p, with resulting homozygous deletion of CDKN2A. This is also characteristic of GBM (particularly its epitheloid variant).29 Complex rearrangements were common but, despite the common hit on chromosome 9, additional events were distinct across the genome (line 1, chormoplextic event 9q-5q and chromothryptic event 12q; line 2, chormoplextic events 9q-21 and 11-17-20; line 3, distinct chromothryptic events on 8p, 9q, 16, and 19). This evidence concerns the gene CDKN2A and glioblastoma.