Multivariate logistic regression analysis (Table 3) revealed that age (OR, 1.06; 95% CI: 1.04–1.08, p ​= ​1.4 ​× ​10−8), hypertension (OR, 4.21; 95% CI: 2.41–7.47, p ​= ​1.4 ​× ​10−8), smoking (OR, 5.63, 95% CI: 2.91–11.31, p ​= ​5.3 ​× ​10−7), triglycerides (OR, 1.002; 95% CI: 1.00–1.003, p ​= ​0.0083), HDL cholesterol (OR, 0.96; 95% CI: 0.94–0.98, p ​= ​8.0 ​× ​10−5), FH mutation (OR, 2.32; 95% CI: 1.07–5.05, p ​= ​0.03), and Achilles tendon thickness ​≥ ​9.0 ​mm (OR, 1.99; 95% CI: 1.01–3.02, p ​= ​0.04) were independently associated with the presence of CAD. This evidence concerns the gene FH and coronary artery disorder.