Most WNT-related genes (Supplementary Table 4) and both natriuretic peptides demonstrated statistically significant differential expression in at least DCM or ICM, with 12 demonstrating differential expression in both: AXIN2, CREBBP, DAAM2, FZD1, FZD7, NFATC2, NPPA, ROR2, SFRP1, SFRP3, WISP2, and WNT10B. The gene discussed is SFRP1; the disease is familial dilated cardiomyopathy.