Nanoparticle delivery systems, such as liposomal, protein-based (e.g., albumin), and polymeric, have been shown to reduce systemic toxicity compared to free drug, as well as improved target site delivery, leading to increased drug concentration at the tumor site (Senapati et al., 2018; Anselmo and Mitragotri, 2019). This evidence concerns the gene ALB and neoplasm.