COL6A1 and myopathy: Considering that defective regulation of autophagy plays a key role in the muscle pathology of both Col6a1–/– mice and patients affected by COL6-related myopathies (Grumati et al., 2010; Castagnaro et al., 2016), and that its reactivation leads to beneficial effects (Chrisam et al., 2015; Castagnaro et al., 2016), we investigated the effects elicited by Pt administration to Col6a1–/– mice.