COL6A1 and Congenital muscular dystrophy, Ullrich type: Regarding COL6-related myopathies, these approaches were shown to be beneficial both in preclinical studies in Col6a1–/– mice (Grumati et al., 2010; Chrisam et al., 2015) and in a pilot clinical trial in UCMD and BM patients, in which autophagy was successfully promoted through a 1-year-long low protein diet (Castagnaro et al., 2016).