Related studies suggested that early experiences, including the quality and extent of maternal care, exerted long-lasting alterations in social behaviors, anxiety, and fearfulness, along with aberrant HPA axis activity and the expression of brain-derived neurotrophic factor (Levine, 1970; Meaney, 2001; Daniels et al., 2004; Seo et al., 2016; Liu et al., 2017). This evidence concerns the gene BDNF and Anxiety.