Well known transcription factors and or proto-oncoproteins such as c- Myelocytomatosis viral oncogene homolog (MYC), Notch1, beta-catenin, or RAS regulate lncRNAs or are being regulated by lncRNAs in different hematological disorders (38–43), [reviewed in (29, 30, 44)]. This evidence concerns the gene MYC and hematologic disorder.