NEAT1 and chronic myelogenous leukemia, BCR-ABL1 positive: A report from Zeng et al., indicated that NEAT1 expression is downregulated in primary CML cells, but that its expression was rescued in K562 CML cell line when the expression or activity of the BCR-ABL kinase, that typically is present in CML cells as a consequence of the t(9:22) translocation, is blocked (38).