It therefore can be inferred that part of MYC’s oncogenic potential is mediated indirectly through the action of CCAT1 and PVT1. These findings support a role of CCAT1 and PVT1 as dominant oncogenes in AML and suggest that interference with the function of these lncRNAs could represent a new therapeutic tool against MYC driven hematological malignancies (124). The gene discussed is PVT1; the disease is hematologic disorder.