In reply to this criticism, Doose et al. defended MINCR to be a MYC-induced lncRNA by highlighting several lines of evidence: MINCR is up-regulated by MYC in cells that contain MYC-inducible constructs; MYC occupies the promoter of MINCR and expression of MINCR and MYC correlates in a number of different MYC positive B-cell lymphomas (80). The gene discussed is MYC; the disease is B-cell non-Hodgkin lymphoma.