Although a significant decrease in the expression of circular noncoding RNA from versican (circ_VCAN, hsa_circ_0073237) in irradiated U87 and U251 cells by 13 h post-irradiation was demonstrated (4–5- and 8–9-fold, respectively), it was significantly up-regulated in radioresistant glioma tissues compared with the radiosensitive tissues. The gene discussed is VCAN; the disease is central nervous system cancer.