BRIP1 and thyroid gland carcinoma: Interestingly, results obtained for variant c.316C>T in BRIP1 gene of ID306 patient's family (Figure 3) shown that, only the sister's patient with cancer history (breast cancer at 42 years of age and thyroid cancer at 53 years of age) carried the c.316C>T variant (two other siblings without cancer history were tested).