HECTD4 and nonpapillary renal cell carcinoma: By contrast, the multivariate cox analysis revealed 12 DMGs (CETN3, DCAF7, GPX4, HNRNPA0, NUP54, SERPINB1, STARD5, TRIM52, C4orf3, C12orf51, C17orf65, and C21orf45) significantly affected overall survival of ccRCC patients (Table 1).