By contrast, the multivariate cox analysis revealed 12 DMGs (CETN3, DCAF7, GPX4, HNRNPA0, NUP54, SERPINB1, STARD5, TRIM52, C4orf3, C12orf51, C17orf65, and C21orf45) significantly affected overall survival of ccRCC patients (Table 1). This evidence concerns the gene ARLN and nonpapillary renal cell carcinoma.