HNRNPC and central nervous system cancer: To verify whether HNRNPC played an important role in the development and progression of glioma, we firstly evaluated its mRNA expression level in glioma (n = 116) and normal brain (n = 28) tissues by RT-PCR, which indicated that HNRNPC expression was upregulated in glioma tissues compared with normal brain tissues (Figure 7A, p < 0.01).