CRLF2 and acute lymphoblastic leukemia: CRLF2 expression was identified in 123 of 264 patients (24% of children with NCI standard risk and 60% of adolescence). A total of 154 patients (30 with CRLF2 and 124 patients without CRLF2 rearrangement) with Ph-like ALL underwent one or more different types of NGS, like transcriptome sequencing, whole genome sequencing, and whole-exome sequencing.