Standard blood tests such as white blood cell (WBC) count, neutrophil count, C-reactive protein (CRP), bilirubin, alanine transaminase (ALT), and albumin have been used as markers for acute appendicitis, and in recent years novel blood markers have been proposed such as procalcitonin, interleukin-6 (IL-6), serum amyloid-A (SAA), granulocyte colony-stimulating factor (G-CSF) and calprotectin as markers for acute appendicitis [3-10]. This evidence concerns the gene CRP and appendicitis.