CD4 and Opportunistic infection: This multicenter cohort study across countrywide recruiting HIV-infected patients aged ≥14 years old revealed that the rates of treatment failure were 23.3% and 33.9% at 6 and 12 months with risk factors for treatment failure were presence of tuberculosis, presence of opportunistic infection, low CD4 cell count of <50 cells/μL, and high viral load of >5 log10 copies/mL [6].