Also, this isoflavone at the doses of 20 and 40 μmol/L reduced the expressions of MMP‐2 and MMP‐9 via PI3K/Akt signaling pathway in TNBC cell lines (MDA‐MB‐231 and 4T1) and inhibited the invasiveness of these BC cells (Zhou et al., 2014). The gene discussed is AKT1; the disease is breast cancer.