HIF1A and cancer: It can be seen from the figure that the main processes of XXMD in treating CIS include herpes virus infection pathway, cancer microRNAs, ovarian steroid hormones, NF-кB signaling pathway, Th17 cell differentiation pathway, HIF-1 signaling pathway, folate biosynthesis pathway, galactose metabolism, fructose and mannose metabolism, and so on, which are closely related to the signal pathways of CIS.