On the other hand, there was no GWAS on the association between cathepsin B/L (CTSB/CTSL) variants and viral infections, and only one GWAS identified a variant (rs4932178, T) in Furin promoter that was linked to Furin upregulation in hepatitis B patients (Lei et al., 2009). The gene discussed is CTSB; the disease is viral infectious disease.