However, as far as myeloid suppressor cells are concerned, miR-34a resembles a tumor suppressor, since miR-34a-mimic transfected into a murine colorectal carcinoma cell line, CT26 cells, leads to a lower induction of myeloid precursor cells into Gr1+CD11b+ cells, the phenotype of MDSC with immunosuppressive activity, in mice (103). Here, ITGAM is linked to neoplasm.