C4A and schizophrenia: In contrast, C4 protein expression was altered according to inflammatory subgroup (F = 4.59, df = 44,2, p = 0.015) but surprisingly, C4 protein was increased in the low inflammatory/schizophrenia subgroup compared to both the high inflammatory/schizophrenia subgroup (62.2%, p = 0.005) and compared to the control group (28.8%, p = 0.026) (Figure 5F).