When analyzing by inflammatory subgroup, C3 mRNA (F = 5.51, df = 50,2, p = 0.007, covaried for age) (Figure 5B) and C4 mRNA (F = 6.88, df = 49,2, p = 0.002) (Figure 5C) were both significantly elevated in the high inflammatory/schizophrenia subgroup compared to the control group (54.9% and 37.3%, respectively, both p = 0.004), and compared to the low inflammatory/schizophrenia subgroup (72.7%, p = 0.004 and 57.6%, p = 0.001, respectively). The gene discussed is C3; the disease is schizophrenia.