According Kaplan–Meier survival analysis of data received from TCGA, expression of ENHO gene do not have a significant impact on the survival profile of patients with adrenocortical carcinoma (logrank p = 0.27) (Figure 12C), however elevated expression of GPR19 leads to a statistically significant decrease in survival (logrank p = 0.0008), suggesting that high expression of GPR19 could constitute a negative prognostic factor of disease progression. The gene discussed is GPR19; the disease is adrenal cortex carcinoma.