Additionally, TRPM2, TRPM7, and TRPC1 activity have been also correlated with MMP2 production in gastric, lung, pancreatic and thyroid cancer (Asghar et al., 2015; Rybarczyk et al., 2017; Liu et al., 2018; Almasi et al., 2019). This evidence concerns the gene TRPM7 and thyroid gland carcinoma.