The activation of PPARα is also considered to be beneficial to atherosclerosis, myocardial ischemia-reperfusion and hypertension (Diep et al., 2004; Bulhak et al., 2006; Ichihara et al., 2006; Tordjman et al., 2007; Pawlak et al., 2015). This evidence concerns the gene PPARA and atherosclerosis.