As expected, si‐FRAS1 treatment did not change the proliferation of SW620 and HT29 cells, and the proliferation of CRC cells transfected with circ102049 + si‐FRAS1 was also not influenced in comparison with those transfected with circ102049 (Fig. S2B–E). The gene discussed is FRAS1; the disease is colorectal carcinoma.