AGO2 and colorectal carcinoma: To confirm further our hypothesis of ceRNA, a series of experiments including the luciferase activity assay, FISH co‐localization by confocal scan imaging, anti‐Ago2 RIP assay and RNA pull‐down analysis all strongly confirmed the direct binding of circ102049 with miR‐761 or miR‐192‐3p in CRC cells.