FGF21 and type 2 diabetes mellitus: To confirm this idea, we first divided HC and T2D patients in three subgroups according to their BMI (normal weight, overweight, and obese) and we observed that the levels of FGF21 were similar between HC and T2D in each BMI subgroup, while FGF21 levels were significantly higher in overweight and obese subjects with respect to normal weight group in both HC and T2D (Table 2).