SQSTM1 and neoplasm: Conversely, downregulation of ATG7 reduced m-THPC-PDT-induced autophagy in tumor tissues, as revealed by the m-THPC-PDT-induced increase in MAP1LC3B-II protein expression and a decrease in SQSTM1/p62 expression that could be counteracted by ATG7 downregulation (Fig. 6B).