In the process of screening patients with the clinical phenotype of STGD1, we also detected the variants of other pathogenic genes instead of ABCA4 related to macular degeneration in another three Chinese families, namely, GUCY2D (c.2513G > A), PDE6C (c.967 T > C and c.1579C > T), and POC1B (c.1153G > A and c.458C > T). Here, ABCA4 is linked to macular degeneration.