OGG1 and breast carcinoma: There are a number of clinical studies in agreement with our results, indicating that the mutant genotypes of OGG1 have higher DNA damage and lower repair capacity of 8-OHdG than wild-type genotype[25,26], which is associated with the risk of lung cancer[26], type 2 diabetes[27], breast cancer[28] and nasopharyngeal carcinoma[29].