IL4 and cancer: IL-4 is an anti-inflammatory cytokine, which is related to regulating immune cells, cancer and trophic responses (Granja et al. 2009; Shamoun et al. 2018; Oviedo-Boyso et al. 2007) found that when cows develop bacteria-induced inflammation, the levels of pro-inflammatory cytokines like IL-1β, IL-2 and IL-6 in the body increased, and the overexpression of pro-inflammatory factor caused tissue damage.