Among laboratory parameters, the modified Glasgow Prognostic Score (GPS)7,8, neutrophil-to-lymphocyte ratio (NLR)9–13, platelet-to-lymphocyte ratio (PLR)14, C-reactive protein albumin (CRP/Alb) ratio15,16, and prognostic nutritional index (PNI)17, have been reported to be predictive factors of OS in patients with pancreatic cancer. This evidence concerns the gene ALB and familial pancreatic carcinoma.