Here, we demonstrate that K8- as well as K-16 peptides (containing 8 and 16 lysine residues with dissociation constants of 102 nM and 11.6 nM for phosphatidylserine, respectively) immobilized on magnetic beads can capture small EVs (< 0.2 μm) from culture supernatants of MCF7 human breast cancer cells. This evidence concerns the gene KRT16 and breast cancer.