The 52 mutations were found in the following genes; PIK3CA (n = 19, 34.5% of the 55 tumours), KRAS and TP53 (n = 5 each, 9.1%), PTEN (n = 4, 7.3%), FBXW7 (n = 3, 5.5%), RB1 and GNAS (n = 2 each, 2.2%), as well as in AKT1, FGFR3, APC, ATM, CTCNB1, FGFR, ERBB4, KDR, KIT, NPM1, SMAD4 and STK11 (n = 1 each, 1.8%). This evidence concerns the gene RB1 and neoplasm.