CD4 and neoplasm: Notably, the effect of Acsl3 loss on the different immune cell populations was tumor specific; as in the healthy Pdx1-CreERT2;p53flfl;Acsl3+/+ and Pdx1-CreERT2; p53flfl; Acsl3−/− mice, we did not detect differences in the total number of T cells (CD45+/CD3+), CD4+ T cells (CD45+/CD3+/CD4+), or CD8+ T cells (CD45+/CD3+/CD8+) (fig.