In their clinical trial of a SDC2 methylation test in detecting CRC, Han et al. also recruited 23 patients with gastric cancer and 10 patients with liver cancer and showed that 30.4% of gastric cancer patients (7/23) and 30% liver cancer patients (3/10) were tested positive for SDC2 methylation [29]. This evidence concerns the gene SDC2 and colorectal carcinoma.