A volcano map (Fig. 1a), boxplots (Fig. 1b), and a heatmap (Fig. 1c) indicated that 20 ARGs (BCL2, CAPN2, CCR2, CDKN1A, FAS, FKBP1B, GABARAP, HSPB8, ITPR1, MAP1LC3C, NKX2-3, NRG1, NRG2, NRG3, PINK1, PRKN, SESN2, TMEM74, TNFSF10, and TP53INP2) were downregulated while 16 ARGs (ATG9B, ATIC, BCL2L1, BID, BIRC5, CAPN10, CD46, CDKN2A, EIF4EBP1, ERO1A, HSP90AB1, IFNG, MYC, SPHK1, TP73, and VEGFA) were overexpressed in colon tumor tissues. The gene discussed is HSP90AB1; the disease is colonic neoplasm.