The results were similar to those of Zhang et al. In their study on the association between preeclampsia HLA-A gene polymorphism and preeclampsia, there was no significant difference in HLA-A allele between preeclampsia group and control group (P (c) > 0.05) [13].But we still observed that the frequency of HLA-A * 24: 02 gene in pregnant women and fetuses in the preeclampsia group is about 10% higher than that in the control group. The gene discussed is HLA-A; the disease is preeclampsia.