In conclusion, our data highlight the maintenance by the cell line of the genes’ expression parameters typical of OSA, that is characterized by overexpression of TP53, ErbB2, IL8 and a discontinuous expression of PTEN. In addition, this cell line demonstrated the ability to interact with an infectious stressor such as ST by suggesting the D-17 as a possible in vitro model for the preliminary evaluation of new therapeutic approaches based on the use of bacteria. The gene discussed is CXCL8; the disease is obstructive sleep apnea syndrome.