This chemokine is known for its pro-inflammatory activity in vivo and in vitro, chemotactic on neutrophils, eosinophils, basophiles and immune cells, angiogenetic [41] and is, with VEGF, PD-ECGF, bFGF and TNFa, one of the tumor molecules derived from macrophages and associated with neo-angiogenesis. This evidence concerns the gene TNF and neoplasm.