INS and staphylococcus aureus infection: Analysis of all significantly upregulated genes identified signalling pathways including HIF-1 (p = 0.002) and PI3K-Akt (p = 0.005), metabolism (glycolysis p = 0.006; fructose and mannose metabolism p = 0.04), insulin resistance (p = 0.01), and an increased immune response (Staphylococcus aureus infection p = 0.007; HTLV-I infection p = 0.02; Intestinal immune network for IgA production p = 0.05) (Table 2).