IARS1 and gestational diabetes: This result can also be transferred to the gender specific subgroups, even though the difference is only significant in the male subgroup (male GDM vs. control: median IRS 1.0 vs. 3.0, p = 0.001 female median IRS 1.0 vs. 2.0; p = 0.53, Figure 2 and Table 1).