CXCL1 and neoplasm: Quantitative RT-PCR performed on the tumor tissue revealed an overall upregulated expression of CXCL1 transcripts in the tumor tissues obtained from mutants with the R72 SNP thus indicating that the mutants with R72 SNP maintain CXCL1 expression in vivo while the mutants with the P72 SNP have a reduced CXCL1 expression (Figure 4B).