PRRT2 mutations can cause paroxysmal movement disorders, including paroxysmal kinesigenic dyskinesia (PKD) [9,10], some cases of paroxysmal non-kinesigenic dyskinesia (PNKD), and paroxysmal exercise-induced dyskinesia (PED) [11], as well as the childhood epilepsy/seizure disorders benign familial infantile epilepsy (BFIE) and infantile convulsions and choreoathetosis (ICCA) syndrome [12,13]. This evidence concerns the gene PRRT2 and benign familial infantile epilepsy.