Consistent with these studies, Gregorieff and colleagues demonstrated that inducible Yap inactivation (Yapfl/fl associated with a Villin-CreERT2 construct allowing for a tamoxifen-inducible deletion of Yap) impairs recovery of the intestinal epithelium after exposure to ionizing radiation and abolishes adenomas in ApcMin mice [34]. The gene discussed is YAP1; the disease is adenoma.