GO enrichment of DEGs revealed that they were mostly enriched in glycosaminoglycan binding,[15] cargo receptor activity,[16] and organic acid binding[17]; KEGG enrichment showed predominant functional enrichment in malaria,[18] cell cycle,[19] and IL-17 signaling pathway.[20] GSEA showed that NSCLC was associated primarily with the citrate cycle (TCA cycle),[21] RNA degradation,[22] and Pyrimidine metabolism pathway.[23] Previous studies have shown that these GO, KEGG, and GSEA pathways play important roles in the development and progression of tumors. Here, IL17A is linked to malaria.