To see whether RD1 was responsible for the alterations in hematopoiesis, we infected mice with H37Rv:ΔRD1 and found no difference between Mtb-ΔRD1, Mtb, and BCG in expanding LKS or HSC populations 28 days post-infection (Figures 1M, 1N, and S1F–S1H). This evidence concerns the gene PDE6B and infection.