IL1B and arthritic joint disease: IL‐38 binds to the IL‐36 receptor (IL‐1R6) and exhibits anti‐inflammatory properties, for example by reducing the Candida albicans induced T helper (Th) 17 response in peripheral blood mononuclear cells (PBMC) and by reducing inflammation, IL‐1β, and IL‐6 in murine models of arthritis [3, 4].