SP140 and bacterial infectious disease: Necrotic pulmonary lesions are prominent in mice bearing a hypomorphic allele of Sp140 in the “Super susceptibility to tuberculosis 1 (Sst1)” locus (Kramnik et al., 2000) that impairs the ability of Sp140 to suppress the type I IFN response during intracellular bacterial infections (Ji et al., 2020Preprint).