Some researcher applied JNK phosphorylation inhibitor which partially reversed the ER stress or ROS‐induced apoptosis in Bcr/Abl‐positive chronic myelogenous leukaemia cells,45 which indicated that JNK phosphorylation was critical for ER stress or ROS‐induced apoptosis.46 This evidence concerns the gene MAPK8 and chronic myelogenous leukemia, BCR-ABL1 positive.