OCA1 (OCA1A, OMIM 203100; OCA1B, OMIM 606952), OCA2 (OMIM 203200), and OCA3 (OMIM 203290) are the most common subtypes of nonsyndromic OCA, caused by homozygous or compound heterozygous variants in the tyrosinase gene (TYR, OMIM 606933), OCA2 melanosomal transmembrane protein gene (OCA2, OMIM 611409), and tyrosinase‐related protein 1 gene (TYRP1, OMIM 115501), respectively.3, 4. The gene discussed is OCA2; the disease is oculocutaneous albinism.