PRP4K and non-small cell lung carcinoma: In order to validate these findings, we knocked down lncRNA MRUL expression and detected RNA splicing regulators expression in NSCLC cell, including RBM25, RBM39, RBM5, RNPC3, SUGP2, THOC1, ACIN1, PRPF3, PRPF38B, PRPF4B, SRSF11, and SRSF2 (Figure 8(a)).