In order to validate these findings, we knocked down lncRNA MRUL expression and detected RNA splicing regulators expression in NSCLC cell, including RBM25, RBM39, RBM5, RNPC3, SUGP2, THOC1, ACIN1, PRPF3, PRPF38B, PRPF4B, SRSF11, and SRSF2 (Figure 8(a)). Here, RBM39 is linked to non-small cell lung carcinoma.