Li et al. (2018) found that PAQR3 inhibits cell proliferation and cell cycle transition, while promoting apoptosis in NSCLC cells through the PI3K/AKT signaling pathway. The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases contain a large number of high-throughput sequencing results, while Oncomine, Timer, and Ualcan database results are derived from TCGA and GEO data. We used the database in advance to demonstrate that PAQR3 expression is increased in NSCLC tissues. This is contrary to the results reported by Liang et al. (2017). This evidence concerns the gene PAQR3 and non-small cell lung carcinoma.