Elevated levels of pro-inflammatory cytokines such as TNFα, IL-1, IL-12, IL-6, and IL-2 have been linked to chorioamnionitis (Negishi et al., 1996; Holst et al., 2007; Berry et al., 2011; Revello et al., 2016) and therefore elevated levels of these cytokines serve to identify potential pregnancy complications. The gene discussed is TNF; the disease is chorioamnionitis.